Contact: [email protected]
* Studie on hold of geen beschikbare plaatsen
| Title | Tumor type | Line | Study information |
|---|---|---|---|
| Regina | Rectal | Neoadjuvant | Regorafenib + nivolumab + short course RT in intermediate risk stage II-III |
| AZUR-2 | CRC | Neoadjuvant | Rand. study of perioperative Dostarlimab mono vs. SOC (surgery + adj chemo) in T4N0 or Stage III dMMR/MSI-H resectable CRC |
| IMCODE003 (GO44479) | Pancreas | Adjuvant | Autogen cevumeran IV + atezo + mFOLFIRINOX vs. mFOLFIRINOX; screening before surgery |
| Nalpac | Pancreas | 2L | Naliri vs Nalirinox. PD after 1st line gemcitabine mono or gem/abraxane |
| Stereopac | Pancreas | Neoadjuvant | preop mFOLFIRINOX (or gem/NabP) +/- SBRT in borderline resectable |
| Mountaineer-03 (SGNTUC-029) | CRC | 1L | Tucatinib+trastuzumab + mFOLFOX6 vs. mFOLFOX6 +/- bevacizumab/cetuximab in HER2+, RAS wt CRC |
| TT420C2308 (FIRST-308) | Cholangio | >1L | Tinengotinib (PO) vs. Physician’s choice therapy; prior FGFR inhibitor required |
| BI1438-0007 (DAREON-7) | NEC | 1L | BI764532 + etoposide + platinum in DLL3+ (phase 1) |
| IL15 TransDC* | Pancreas | >1L | IL15 TransDC vaccin (6 vaccinations, concomitant anti-cancer therapy possible 7D after V2; phase 1) |
| M24-311 | mCRC | 2L | ABBV-400 + 5FU/LV + beva vs FOLFIRI + bevacizumab |
| D7025C00001 (ARTEMIDE-Biliary01) | BTC | adjuvant (1L) | Rilvegostomig Q3W + capcetabine vs placebo + capcetabine |
| 61186372COR3001 (OrigAMI-2) | Left-sided CRC | 1L | Amivantamab vs cetuximab + folfox of folfiri |
| 61186372COR3002 (OrigAMI-3) | CRC | >1L | Amivantamab vs cetux/beva + folfiri rando 1:1 |
| JZP598-302 | BTC | 1L | zanidatamab + gem/cis + PD-1/L1 (=SOC) vs SOC |